Nuphorin

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Nuphorin is an anxiety-anxiety dietary supplement that contains nutrients such as a B vitamin complex, ashwagandha, and more.

Nuphorin is an anti-anxiety supplement manufactured by Vitavana, a dietary supplements manufacturing firm based in Seattle, Washington at 4509 Interlake Ave N #181. Nuphorin has been on the market for some time now and has developed a significant following and sales profile. To that end, Natural Anxiety Meds has compiled this information page about the supplement in order to give you an in-depth analysis of the ingredients of Nuphorin, its theoretical and actual efficacy, available product reviews, and directions on how to purchase it.

Analysis of Ingredients

Nuphorin contains the following active ingredients: Ashwagandha (7% extract), GABA, Chamomile (4:1 extract), 5-HTP, DMAE Bitartrate, Vitamin B1, Vitamin B2, Niacinamide (Vitamin B3), Vitamin B6, Folic Acid (Vitamin B9), Vitamin B12, Calcium, and Magnesium. Other ingredients include: Cellulose, Magnesium Stearate, Silicon Dioxide and Vanilla Flavor (manufacturer claims this ingredient is added to modulate the product’s aroma).

The following table will provide a brief summary of the function of each of these ingredients, as well as a link to scientific literature which explains their role in mental health. Additionally, if we have compiled an entry for a given ingredient on the site, we will provide a link to a document that elaborates on its role in anti-anxiety processes.

Name of Ingredient Description
Ashwagandha From the Indian Ayurveda tradition comes Ashwagandha, also known by its Latin botanical name “Withania somnifera.” Preliminary studies have found support for the use of ashwagandha for a variety of medical conditions; however, until a double-blind peer-reviewed study is available in the scientific literature, it is important to understand that there is no conclusive scientific support for its use in anxiety. Nonetheless, initial studies have proven promising in this regard.
GABA GABA is a neurotransmitter that plays a number of important roles in regulating neurological and physical health. Although it cannot by itself cross the blood-brain barrier, GABA can be combined with our compounds in order to reach the central nervous system. In situations where GABA crosses the blood-brain barrier, it has been found to have a positive effect on mood.
Chamomile In a study conducted by the University of Pennsylvania, chamomile was found to have a moderately beneficial effect upon individuals suffering from mild Generalized Anxiety Disorder (GAD). However, the results of this study have not since been replicated. Consequently, it appears that there is a tentative beneficial effect of chamomile on anxiety and other psychological conditions.
5-HTP 5-HTP is an amino acid that may play a role in regulating mental health. Although studies which indicate its efficacy with respect to anxiety symptoms are lacking, meta studies have been undertaken which conclude that there may be a tentative benefit in consuming 5-HTP supplements.
DMAE Bitartrate Preliminary studies have found that DMAE Bitartrate may have an effect on overall sense of well-being and other psychological ailments related to anxiety and depression. Although more conclusive studies are necessary, it may indeed be effective in treating anxiety symptoms.
Vitamin B1 Vitamin B1 – also known as thiamine – is an essential vitamin and is found within almost all cells in the human body. A deficiency of it can lead to major physiological problems, including Alzheimer’s Disease.
Vitamin B2 Vitamin B2 – also known as riboflavin- is an essential vitamin and is found within almost all cells in the human body. A deficiency of it can lead to major physiological problems, including inflammation, skin rashes, and more.
Niacinamide (Vitamin B3) Vitamin B3 – also known as niacin – is one of the essential nutrients that your body needs in order to function properly. Its deficiency can lead to a number of major illnesses.
Vitamin B6 Vitamin B6 refers to a set of essential nutrients that provide the necessary resources for very important biological functions like gene expression. A deficiency can lead to very negative outcomes, sometimes beginning with marked confusion.
Folic Acid (Vitamin B9) Vitamin B9 – also known as folic acid – has been found to be a key factor in mental illnesses like depression. Individuals who experience a deficiency of vitamin B9 can potentially acquire psychological problems like anxiety and depression.
Vitamin B12 Vitamin B12 plays a key role in regulating the central nervous system, the brain, blood chemicals, and more. Without it, you simply wouldn’t be alive. A deficiency of vitamin B12 can lead to mania and psychosis, among other psychological and neurological illnesses.
Calcium Although there is not much scientific literature pertaining to the effects of calcium deficiency on mental health, it is important nonetheless to have sufficient calcium intake to keep the skeletal and nervous systems in good shape.
Magnesium Certain vital nutrients and minerals such as magnesium are vital for regulating neurochemical processes. One of the most important minerals for this type of regulation is magnesium, known by its chemical shorthand “Mg.”

It is important to note that while many of these ingredients have undergone scientific studies in order to determine their usefulness in treating mental health problems such as anxiety, no studies exist to the best of our knowledge that definitively prove an anxiolytic effect from the combination of each of these ingredients. Given this lack of scientific literature, we definitely advise you to consult with your doctor or other trusted medical professional prior to taking Nuphorin for your anxiety condition.

Supporting Scientific Evidence

Although there currently exist no scientific studies which specifically verify the efficacy of Nuphorin, there are numerous studies which support the individual ingredients used in the supplement. However, we advise that you talk to your doctor prior to using Nuphorin or any other anti-anxiety supplement, as some ingredients may interfere with other medications. For scientific studies which support the individual ingredients used in Nuphorin, please see the previous table for more information.

Side Effects

Since the FDA does not regulate dietary supplements – regardless of the health benefits they claim to provide – we do not have any exact information about the side effect profile for Nuphorin. However, based on our analysis of Amazon reviews for the product as well as from our own testing, we can cautiously advise you of the following possible side effects:

  • Some customers have reported sleepiness and drowsiness when first trying out the supplement. This side effect does not appear to last, however.
  • Additionally, some customers have reported that the product has no effect at all on their anxiety symptoms. Naturally, your individual body chemistry will play an important rule in determining whether or not it works for you.

Should more information become available about Nuphorin’s possible side effects, we will update this list as soon as possible.

Customer Reviews

Based on customer reviews at Amazon and elsewhere, it appears that the majority of customers who opt to purchase Nuphorin tend to be happy with their purchase. Of course, reviews can be doctored, so it is important to keep in mind that the product may not work for everybody – regardless of how many 5-star reviews there may be. As always, use Nuphorin and other dietary supplements at your own discretion.

Where to Purchase Nuphorin

Nuphorin can be purchased on Amazon. To go to its product description page, please click on the following box:


Have you tried taking Nuphorin for your anxiety condition? Was it effective in reducing the intensity of your symptoms? Please leave us a short comment below – it may just help someone who is looking for the solution to their own anxiety symptoms.

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