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Tranquilene is a supplement created by Tranquility Labs LLC. It is an anxiolytic supplement intended for daily use. The manufacturer claims that the supplement contains no GMO’s and that it is manufactured in the United States of America.

In this article, we will examine the manufacturer description of the product and perform an analysis on its ingredients. Tranquilene contains the following ingredients: Calcium, Vitamin B1, Vitamin B3, Vitamin B6, Vitamin B5, Vitamin B12, Magnesium, Passion Flower, GABA, L-Tryptophan, Ashwagandha, Bacopa Monnieri, L-Theanine, Green Tea Extract. We will also look at side effects and safety information for the product.

Manufacturer Description

“Tranquilene Total Calm ( is an all-natural anti-stress, anti-anxiety, anti-panic supplement for daily use. Tranquilene brings together the best in Eastern herbal healing practices with the most current in Western natural medicine to help eliminate many common imbalances that lead to anxiety. Most of the 14 ingredients in the formula are clinically proven to reduce anxiety. The key to Tranquilene’s effectiveness is its two-part approach that works toward fast anxiety and panic relief as well as long-term mood support. The ingredients in the formula provide crucial nutrients to the systems in your brain responsible for maintaining a calm mood, and work to restore balance, creating a calmer, more confident you.”

Analysis of Ingredients

Tranquilene contains the the following ingredients:

Calcium Although there is not much scientific literature pertaining to the effects of calcium deficiency on mental health, it is important nonetheless to have sufficient calcium intake to keep the skeletal and nervous systems in good shape.
Vitamin B1 This vitamin is also known as “thiamine.” A thiamine deficiency wreaks havoc on the nervous system.
Vitamin B3 Also known as “niacin.” It is an essential vitamin for both physical and psychological health. The body uses niacin to process food into energy and create stress and sex hormones. It is known that increased levels of niacin lead to lower rates of Alzheimer’s. A deficiency of this vitamin can lead to fatigue, vomiting, and depression.
Vitamin B6 B6 regulates a number of important physiological functions, including amino acid metabolism, neurotransmitter synthesis,h istamine synthesis, hemoglobin synthesis, and gene expression.
Vitamin B5 Also known as pantothenic acid. It has a number of important biological roles at the enzyme level. A deficiency of pantothenic acid has been linked to fatigue and apathy, though more research is needed. A large deficiency can be deadly.
Vitamin B12 Supports and maintains the body’s blood and nerve cells, as well as performing other critical genetic functions. It is essential for all primary biological functions.
Magnesium An abundant resource in the body, Magnesium is necessary for all basic properties of life.
Passion Flower The Passionflower (Passiflora incarnata) is a species of passionflower with anxiolytic and sedative properties. Read more
GABA Also known as gamma-aminobutyric acid. GABA is a neurotransmitter responsible for a number of critical nervous system functions. Scientific studies have shown that increasing the amount of GABA in the nervous system will have anti-anxiety effects.
L-Tryptophan Tryptophan is an amino acid which acts as one of the biological building blocks for compounds such as serotonin, niacin, and auxin.
Ashwagandha This herb comes from the Indian Ayurvedic traditional medicine tradition. A number of scientific studies have shown that Ashwagandha supports physiological and psychological health and increases energy levels. Read more
Bacopa Monnieri Bacopa Monnieri has been used for centuries as a brain tonic, and it is said that it has a number of uses that can help the ease problems associated with the nervous system and brain. Read more
L-Theanine A Japanese study has suggested that the oral intake of l-theanine provides anti-stress benefits by inhibiting cortical neuron excitation. L-theanine allows for enhanced awareness and mental clarity without drowsiness or agitation. Read more
Green Tea Extract Another ancient anxiety remedy is a derivative of green tea leaves.

Tranquilene Side Effects

According to the manufacturer’s website, Tranquilene should not be taken in conjunction with blood thinners, muscle relaxants, sleep or anxiety medicines, pain medicines, seizure medicines, medicines that cause drowsiness, alcohol, and MAOI-class drugs.

The manufacturer also lists the following possible side effects:

  • drowsiness
  • fatigue
  • stomach upset
  • headache
  • morning grogginess (if taken before bed)
  • increased effects of sedative drugs
  • lowering of blood pressure

It is important to note that no clinical trials have been commenced to study this supplement, and you should consult a doctor before incorporating it into your treatment regimen.

Where to Buy

Tranquilene is available for purchase directly from Amazon:

Have you tried Tranquilene? What was your experience? Leave a comment below.

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